Paralkar Lab, ribosome biogenesis, ribosome hematopoiesis, leukemia, transcription, epigenetics

Publication in Leukemia

Publication of “PHF6 suppresses self-renewal of leukemic stem cells in AML” in LEUKEMIA by Sapana Jalnapurkar, PhD (post-doctoral fellow) and Aishwarya Pawar (PhD student) as co-first authors, with contributions from Subin George, Charles Antony, Patrick Somers, Jason Grana, Victoria Feist from the Paralkar Lab, in collaboration with Sandeep Gurubuxani from the University of Chicago.

Talks at UPenn Heme Malignancies Research in Progress meeting

Sapana Jalnapurkar, Post-Doctoral Researcher, and Aishwarya Pawar, PhD Student, present talks on work in mouse and human cell line models on the role of the chromatin regulation PHF6 in leukemia at the UPenn Heme Malignancies Research in Progress meeting.

Grant from National Institutes of Health

The Paralkar Lab is awarded an R01 grant by the National Heart, Lung, and Blood Institute (NHLBI) of the National Institutes of Health (NIH) to study the role of the chromatin binding and nucleolar protein PHF6 in the regulation of HSC self-renewal and myeloid differentiation.