Paralkar Lab, ribosome biogenesis, ribosome hematopoiesis, leukemia, transcription, epigenetics

Publication in Leukemia

Publication of “PHF6 suppresses self-renewal of leukemic stem cells in AML” in LEUKEMIA by Sapana Jalnapurkar, PhD (post-doctoral fellow) and Aishwarya Pawar (PhD student) as co-first authors, with contributions from Subin George, Charles Antony, Patrick Somers, Jason Grana, Victoria Feist from the Paralkar Lab, in collaboration with Sandeep Gurubuxani from the University of Chicago.

Hematology-Oncology fellow awarded fellowship award

Putzer Hung, MD/PhD, Hematology-Oncology fellow, is awarded the 2024 Marlene Shlomchik Fellowship in Cancer Research from the University of Pennsylvania Abramson Cancer Cancer to study rRNA transcription and the rDNA-associated proteome in leukemia.

Talk at Penn Cell and Developmental Biology Retreat

Aishwarya Pawar, Cancer Biology PhD student, presents a talk on chromatin regulation in leukemia, and Charles Antony, Research Associate, presents a poster on rRNA transcription at the Cell and Developmental Biology Departmental Retreat for the University of Pennsylvania Perelman School of Medicine.

Talk at the Heme Malignancies Research in Progress meeting

Charles Antony (Research Associate), Eleanor Sams (Genetics and Epigenetics PhD student), and Victoria Feist (Research Specialist) present talks about ribosomal RNA regulation at the University of Pennsylvania Heme Malignancies Research in Progress meeting.

Poster presentation at CAMB symposium

Aishwarya Pawar, PhD student, presents a poster at the Cell and Molecular Biology Graduate Group Symposium 2023 on regulation of leukemia stemness by the chromatin factor PHF6.

Equipment award from National Institutes of Health

The Paralkar Lab is awarded an equipment award by the National Institute of General Medical Sciences (NIGMS) of the National Institutes of Health (NIH) to purchase a dedicated Sony benchtop SH800 cell flow sorter.

Poster Presentation at Penn CURF

Aleena Alex, UPenn undergraduate student, presents a poster at the Center for Undergraduate Research and Fellowships (CURF) Fall Research Expo on her work on PHD domain point mutations in chromatin regulators in leukemia.

Poster Presentations at ISEH

Post-Doctoral Researcher Charles Antony and graduate student Aishwarya Pawar present posters of their work on chromatin and rRNA transcription regulation in hematopoiesis and leukemia at the International Society of Experimental Hematology 2023 Annual Meeting in New York.

Talk at CAMB Penn Cancer Research Series

Aishwarya Pawar, PhD student, presents a talk on chromatin regulator mutations in acute myeloid leukemia to the Cell and Molecular Biology Graduate Group at the University of Pennsylvania Perelman School of Medicine.

Undergraduate Student Awarded Research Grant

Aleena Alex, UPenn undergraduate student, is awarded the Center for Undergraduate Research and Fellowships (CURF) Award to study PHD domain point mutations in chromatin regulators in leukemia.