Paralkar Lab, ribosome biogenesis, ribosome hematopoiesis, leukemia, transcription, epigenetics

Poster Presentation at Penn CURF

Aleena Alex, UPenn undergraduate student, presents a poster at the Center for Undergraduate Research and Fellowships (CURF) Fall Research Expo on her work on PHD domain point mutations in chromatin regulators in leukemia.

Poster Presentations at ASH

Post-Doctoral Researchers Sapana Jalnapurkar (ASH Restart Award recipient) and Charles Antony (ASH Scholar Award recipient) present posters of their work on chromatin and rRNA transcription regulation in hematopoiesis and leukemia at the American Society of Hematology 2022 Annual Meeting in New Orleans.

Talks at UPenn Heme Malignancies Research in Progress meeting

Sapana Jalnapurkar, Post-Doctoral Researcher, and Aishwarya Pawar, PhD Student, present talks on work in mouse and human cell line models on the role of the chromatin regulation PHF6 in leukemia at the UPenn Heme Malignancies Research in Progress meeting.

Grant from Abramson Family Cancer Research Institute

The Paralkar Lab is awarded a Pilot Research Grant by the Abramson Family Cancer Research Institute to perform a CRISPR tiling mutagenesis screen to dissect ribosome biogenesis regulation in leukemia. This grant is in collaboration with the laboratory of Junwei Shi, Department of Cancer Biology, University of Pennsylvania Perelman School of Medicine.

Collaborative publication in Genes and Development

Publication by laboratory of Stuart Orkin and Max Pimkin of “A distinct core regulatory module enforces oncogene expression in KMT2A-rearranged leukemia” in GENES & DEVELOPMENT, with contribution from Paralkar Lab.

Talks and Poster Presentations at ASH

Vikram Paralkar gives a talk at the Scientific Workshop on Myeloid Development at the American Society of Hematology Annual Meeting 2021. Charles Antony, Post-Doctoral Researcher, and Aishwarya Pawar, PhD Student, present posters on rRNA transcription and chromatin regulation in leukemia.

Poster Presentations at Penn

Charles Antony and Sapana Jalnapurkar, Post-Doctoral Researchers, present posters on ribosomal RNA regulation and leukemia mouse models at the University of Pennsylvania Department of Medicine Research Day 2021.

Presentations at ASH

Sapana Jalnapurkar and Charles Antony, Post-Doctoral Researchers, present oral talk and poster presentation respectively at the American Society of Hematology Annual Meeting 2020.

Grant from American Cancer Society

The Paralkar Lab receives funding through the American Cancer Society Institutional Research Grant to study the role of PHF6 in acute myeloid leukemia.