Paralkar Lab, ribosome biogenesis, ribosome hematopoiesis, leukemia, transcription, epigenetics

Customized genomes for human and mouse rDNA mapping, with annotation files and sample tracks.

This GitHub repository contains publicly accessible human hg19 (GRCh37), hg38 (GRCh38), hs1 (T2T-CHM13), and mouse mm10 (GRCm38), mm39 (GRCm39) genomes optimized for rDNA mapping with an additional chromosome R (chrR). It also contains annotation BED files depicting rDNA promoters, rRNA transcribed region, and intergenic spacer (IGS) regions on chrR, along with positive and negative control tracks (BWs). For details on construction of custom genomes, and for a detailed pipeline to guide rDNA mapping, check out our Bioinformatics Methods paper.