Paralkar Lab, ribosome biogenesis, ribosome hematopoiesis, leukemia, transcription, epigenetics

We are looking for talented researchers from a range of backgrounds, with interests in normal or leukemic hematopoiesis, or in hematopoiesis or leukemia as model systems to interrogate basic mechanisms of gene transcription or ribosome biogenesis. Work in our laboratory encompasses human samples, mouse models, cell lines, molecular biology and biochemical studies, high-throughput assays, and bioinformatic and computational pipelines. Research projects may contain wet-lab or dry-lab components based on the strengths and interests of each applicant.

We are dedicated to improving diversity, and invite applications from groups that are traditionally underrepresented in science.

Graduate Students

We are part of the Cancer Biology (CB) group within the Cell and Molecular Biology Graduate Group (CAMB) at UPenn, and are actively recruiting rotation students for a range of wet and dry-lab projects. Our interdisciplinary work overlaps with interests in multiple other programs, especially Genetics and Epigenetics (G&E) and Developmental, Stem Cell, and Regenerative Biology (DSRB). Students from all departments and graduate groups are invited to contact Vikram if interested in a rotation. (updated Dec 2023)

Post-Doctoral Researchers

We are actively recruiting post-doctoral candidates for an NIH (NIGMS) R35 grant funded position studying regulation of ribosomal RNA transcription in hematopoiesis, and an NIH (NHLBI) R01 grant funded position studying chromatin regulation in normal and leukemic stem cells and myeloid lineage differentiation. Contact Vikram with your CV, a brief description of your research interests, and contact information for three references. (updated Apr 2023)