Paralkar Lab, ribosome biogenesis, ribosome hematopoiesis, leukemia, transcription, epigenetics

Grant from the Abramson Cancer Center

The Paralkar Lab is awarded a Pilot Research Grant by the Abramson Cancer Center to model AML evolution from germline Runx1 mutations. This grant is in collaboration with the laboratory of Nancy Speck, Department of Cell and Developmental Biology, University of Pennsylvania Perelman School of Medicine.

Grant from National Institutes of Health

Charles Antony, Post-Doctoral Researcher, is awarded a Co-Operative Center for Excellence in Hematology (CCEH) Type B grant by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) of the National Institutes of Health (NIH) to study transcription factor dynamics and regulation in primary human bone marrow.

Grant from Abramson Family Cancer Research Institute

The Paralkar Lab is awarded a Pilot Research Grant by the Abramson Family Cancer Research Institute to perform a CRISPR tiling mutagenesis screen to dissect ribosome biogenesis regulation in leukemia. This grant is in collaboration with the laboratory of Junwei Shi, Department of Cancer Biology, University of Pennsylvania Perelman School of Medicine.

Grant from National Institutes of Health

The Paralkar Lab is awarded a Co-Operative Center for Excellence in Hematology (CCEH) grant by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) of the National Institutes of Health (NIH) to model the effect of RUNX1 point mutations on mouse hematopoietic stem and progenitor cells.

Grant from National Institutes of Health

The Paralkar Lab is awarded an R01 grant by the National Heart, Lung, and Blood Institute (NHLBI) of the National Institutes of Health (NIH) to study the role of the chromatin binding and nucleolar protein PHF6 in the regulation of HSC self-renewal and myeloid differentiation.

Grant from National Institutes of Health

The Paralkar Lab is awarded a MIRA R35 grant by the National Institute of General Medical Sciences (NIGMS) of the National Institutes of Health (NIH) to study the regulation of ribosomal RNA transcription in mammalian tissues.

Grant from American Cancer Society

The Paralkar Lab receives funding through the American Cancer Society Institutional Research Grant to study the role of PHF6 in acute myeloid leukemia.